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Dry eyes after laser:
what to really expect.

Dry eyes after laser is the most cited side effect — and the most misunderstood. It is not an inevitable consequence, it is not permanent, and the surgical technique chosen makes an enormous difference.
Dr. Federico Mossa·FMH Ophthalmology·April 2026·7 min read

Almost all patients who come for a consultation ask us the same question: will I have dry eyes after the laser? The honest answer is: yes, probably, for a limited period. But the degree, duration and impact on quality of life depend on the technique used.

Why laser causes temporary dryness

The cornea is one of the most innervated tissues in the body. Corneal nerves — branches of the trigeminal nerve — regulate the blink reflex (eyelid opening and closing) and tear production. Any laser procedure acting on the cornea temporarily interrupts some of these nerve fibres. The result is a transient reduction in corneal sensitivity and, consequently, less stimulation of the lacrimal gland.

It is a neurogenic effect, not damage to the lacrimal gland itself. The gland works — it is the nerve signal that is temporarily reduced.

TransPRK vs LASIK vs SMILE: the difference is in the nerves

The level of post-operative dryness depends directly on the number of nerve fibres interrupted during the procedure.

LASIK — cutting the corneal flap severs the sub-basal nerve plexus across the entire circumference of the flap (diameter 8-9 mm). This is the main mechanism of post-LASIK dryness. Nerve regeneration takes 6-12 months, and in a small percentage of patients, dryness may persist beyond a year, or for life in rare cases.

SMILE — the incision is smaller (2-4 mm) compared to the LASIK flap, so fewer fibres are interrupted. Dryness is generally less than LASIK, but intrastromal dissection of the lenticule still involves deep nerve fibres.

TransPRK SmartSurfACE — no cutting, no flap, no incision. The laser removes the epithelium and superficial stroma in a single pass. The sub-basal nerve plexus is only partially affected by ablation in strong corrections, but is not severed as in LASIK. Nerve regeneration is faster because fibres are not cut but thinned. Dryness is typically milder and shorter.

What to expect in practice

In our experience with TransPRK:

First week: moderate dryness, managed with preservative-free artificial tears every 1-2 hours. The patient feels a "gritty" sensation that decreases day by day.

First month: dryness reduces progressively. Most patients switch to artificial tears 3-4 times a day. Corneal sensitivity is recovering.

Third month: residual dryness is minimal or absent in the vast majority of patients. Artificial tears are used only "as needed" — hours in front of a screen, in air-conditioned environments, on planes.

Sixth month: return to normality for almost all patients. Corneal sensitivity is fully recovered.

Pre-operative risk factors

Not everyone starts from the same level. Certain factors increase the risk of prolonged post-operative dryness: prolonged contact lens wear (which already reduces corneal sensitivity), age over 50 (tear production decreases physiologically), female sex (hormonal factors), blepharitis or Meibomian gland dysfunction, systemic medications (antidepressants, antihistamines, beta-blockers).

These factors are assessed during the diagnostic examination. The MS-39 tomographer includes an advanced tear film analysis based on Placido topography: film regularity and stability are measured and documented. If the patient has significant dry eye before surgery, we treat it first and operate afterwards — or we don't operate.

How we manage the post-operative period

After each TransPRK procedure, the patient receives in their patient portal the complete instructions: eye drop schedule (antibiotic + anti-inflammatory + artificial tears), control appointment timeline, direct contact with the clinic. No paper to lose, no doubts at home.

Post-operative check-ups — included in the procedure fee for 12 months — allow monitoring of corneal regeneration and adjustment of tear therapy if needed. The 5-year guarantee also covers possible enhancements in the very rare cases where the result changes over time.

Transparency as a principle

Post-operative dry eye exists. Denying it would be dishonest. But in real clinical practice — with TransPRK SmartSurfACE, complete pre-operative diagnostics and structured follow-up — it is a transient, manageable and predictable phenomenon. It is not a reason not to have surgery. It is a reason to choose the right technique and the right surgeon.

FOTO
Dr. Federico Mossa
FMH Ophthalmology · Medical Director CEMO
Specialisation University of Oxford. +25'000 procedures.
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Dr. Federico MossaFMH Ophthalmology  ·  Medical Director CEMO since 2011  ·  +25'000 procedures  ·  6 publications: JCRS · JAMA · BJO · Eye · Springer  ·  Updated April 2026
FMHISO 9001/13485+25k procedures4 clinics CH5-year guarantee6 PubMed
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